Intestinal Permeability

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What is the Intestinal permeability test?

Intestinal permeability, also known as leaky gut or leaky gut syndrome, refers to the condition of the intestinal mucosa.

In a healthy state, the intestinal lining is naturally semi-permeable, allowing essential micronutrients to pass through tiny junctions into the bloodstream.

If you are facing issues with your intestinal function, request your initial consultation with us.

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Intestinal linings serving as small gates are selective, preventing undigested food particles, germs, and toxins from passing through.

This mechanism is vital for maintaining the health of the gut and the overall body, as pathogens that cannot traverse the intestinal barrier are eventually eliminated through urine or feces.

Changes in intestinal permeability are associated with various health conditions, including autism, autoimmune disorders, food sensitivities, and inflammatory bowel disease.

The disturbance in the intestinal barrier, known as a 'leaky gut,' can lead to disease by allowing toxic molecules to enter the bloodstream and adversely affect the body.

The lactulose/mannitol test is employed to measure intestinal permeability. This test is recommended for assessing intestinal permeability and malabsorption.

It serves as a valuable tool to monitor improvements or deterioration in permeability due to therapy, disease, or drug use.

Additionally, the test has proven effective in monitoring compliance and the effectiveness of a gluten-free diet in patients with Coeliac disease.

Symptoms of Intestinal Permeability:

  • Digestive issues: bloating, gas, constipation, diarrhoea, nausea, or irritable bowel syndrome (IBS)
  • Food allergies, sensitivities, or intolerances
  • Skin problems: acne, rashes, rosacea, eczema
  • Fatigue
  • Insomnia or other sleep disturbances
  • Brain fog, difficulty concentrating, memory issues
  • Mood imbalances: anxiety and depression
  • Headaches or migraines
  • Chronic muscle or joint pain
  • Frequent illness, slow recovery, and other signs of compromised immune health
  • Seasonal allergies or asthma
  • Hormonal imbalances: irregular periods, PMS, or polycystic ovarian syndrome
  • Autoimmune diseases: Celiac disease, Crohn's disease, rheumatoid arthritis, Hashimoto's thyroiditis, lupus, or psoriasis
  • Fibromyalgia
  • Chronic fatigue syndrome
Gastroenterologist holding illustration of large intestine on light blue background, closeup

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